周光新

简介

周光新，南京大学医学院附属金陵医院骨科副主任，医学博士，博士后。南京大学、东南大学、南京医科大学、南方医科大学硕士生导师。享受军队优秀科技人才津贴，江苏省“六大人才高峰”高层次人才培养对象，江苏省“333”高层次人才培养对象。中国骨科菁英会会员，江苏省骨科青年委员会副主任委员，全军骨科青年委员会副主任委员，全军骨科青年委员会脊柱学组副主任委员，中国抗癌协会肉瘤委员会委员，中国抗癌协会骨肿瘤和骨转移瘤委员会委员，中华医学会骨科分会骨肿瘤学组青年委员，全军骨科专业委员会骨肿瘤学组委员兼秘书，中国抗癌协会肉瘤委员会骨盆肿瘤学组委员，江苏省骨科专业委员会骨肿瘤学组委员兼秘书，原南京军区骨肿瘤学组委员。主持国家自然科学基金两项、全国博士后面上基金、江苏省自然科学基金面上项目，全军青年科技项目、江苏省卫健委项目各一项，第二完成人申请江苏省自然基金及军区基金各一项。2008年赴德国法兰克福风湿病中心及汉堡ENDO CLINIC医院进修。2015年被中国骨科医师协会评为“先进工作者”，获军队科技进步二等奖及江苏省科技进步三等奖各一项，获“刘志红青年医学奖”二次，获三等功一次。在Molecular Cancer、Science Advances、Protein&Cell等SCI杂志发表论文多篇，单篇最高影响因子44.14。主持的基金项目国家自然科学基金面上项目 （81472508）国家自然科学基金青年项目 （81102039）国家博士后自然科学基金面上项目 （2012M512178）江苏省六大人才高峰项目 （2014-WSW-042)江苏省自然科学基金面上项目 （BK20141376）全军青年科技项目 （19QNP038）发表的论文：1.Expression profiles of miRNAs in giant cell tumor of bone showed miR-187-5p and miR-1323 can regulate biological functions through inhibiting FRS2. Cancer Med. 2020 May;9(9):3163-3173.2. Functions of Exogenous RUNX2 in Giant Cell Tumor of Bone In Vitro. Orthop Surg. 2020 Apr;12(2):668-678. 3. MiR-139 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1. Front Biosci (Landmark Ed). 2019 Jun 1;24:1167-1177. 4. Association between Mediterranean diet adherence and colorectal cancer: a dose-response meta-analysis. Am J Clin Nutr. 2020 May 2.5. Efficacy Analysis of Separation Surgery Combined with SBRT for Spinal Metastases-A Long-Term Follow-Up Study Based on Patients with Spinal Metastatic Tumor in a Single-Center. Orthop Surg. 2020 Apr;12(2):404-420.6.Ling Z, Fan G, Yao D, Zhao J, Zhou Y, Feng J, Zhou G, Chen Y. MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2. Exp Ther Med. 2020 Jan;19(1):481-488. 7.MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6.Protein Cell. 2016 May 26.8.Identification of miR-199a-5p in serum as noninvasive biomarkers for detecting and monitoring osteosarcoma. Tumour Biol. 2015 Jun 12.9.miR-16 promotes the apoptosis of human cancer cells by targeting FEAT.BMC Cancer. 2015 Jun 2;15:448.10. Preparation and antitumor activity of a polymer derivative of metrotrexate. The American Joournal of the Medical Sciences.(2012 Oct;344(4):294-9) 11.A microRNA expression signature predicts meningioma recurrence. International Journal of Cancer. (2013 Jan 1;132(1):128-3612. MicroRNAs in osteosarcoma: from biological players to clinical contributors. The Journal of International Medical Research (2013 Feb;41(1):1-12)13.Composite Reconstruction of the Hip Following Resection of Periacetabular Tumors: Middle-Term Outcome. J Arthroplasty. 2013 Mar;28(3):537-42.14.DNA/chitosan nanocomplex as a novel drug carrier for doxorubicin.Drug Deliv. 2009 Apr;16(3):135-44.15.The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma. Front Biosci. 2013 Jun 1;18:1384-91.

擅长

脊柱退行性疾病，脊柱及四肢原发及转移性肿瘤的诊治，复杂骨折等疾病的诊治。