赵建宁

简介

赵建宁，东部战区总医院骨科主任，主任医师，教授，南京大学、第二军医大学、南京医科大学和南方医科大学博士生导师，博士后联系导师，技术三级，文职一级，享受国务院政府特殊津贴和军队优秀人才特殊津贴。江苏省有突出贡献中青年专家，荣立三等功2次。 全军骨科专业委员会副主任委员、关节外科主任委员，全国关节外科委员，髋关节外科工作委员会执委，副组长, 膝关节外科工作委员会委员，全国和全军残疾人学会肢体残疾委员会副主任委员，中国医师协会骨科专业委员，关节外科常务委员，全军运动医学及关节镜学会委员，中国老年学会脊柱关节疾病专业委员会常务委员，华裔骨科学会理事，亚太人工关节学会中国分会理事。江苏省医学会骨科分会主任委员，南京市骨科专业副主任委员，江苏省中西医结合学会骨伤专业副主任委员，南京军区显微外科专业主任委员，南京军区骨科专业副主任委员等。并担任《医学研究生学报》副主编、《中华创伤骨科杂志》、《中国骨与关节损伤杂志》、《中国矫形外科杂志》、《中国骨伤》、《中华解剖与临床》、《The Jourmai of Arthroplasty》中文版杂志等杂志的常务编委和编委。主要研究方向为人工关节置换术后无菌性松动的防治和关节软骨损伤的早期诊断和修复。获国家自然科学基金等课题9项，省部级科技进步奖14项，其中二等奖6项，获国家专利6项，主译或参与编写专著6部，以第一和通讯作者发表论文300余篇，其中SCI论文55篇，总影响因子149.386，最高影响因子11.753。至今已培养31名博士生，114名研究生。 近5年科研情况汇总SCI文章序号论文题目杂志名称作者发表年月卷期页码1Autophagy mediated CoCrMo particle-inducedperi-implant osteolysis by promoting osteoblastapoptosisAutophagyIF 11.753赵建宁201511122358 - 23692Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese populationInternational Journal of Clinical and Experimaental PathologyIF 1.891 赵建宁2015833198-32033The fibroblast expression of RANKL in CoCrMO-Particle-induced osteolysis is mediated by ER stress and XBP1sActa biomaterialiaIF 6.025赵建宁201524 352-3604ER stress mediated TiAl6V4 particle-induced peri-implant osteolysis by promoting RANKL expression in fibroblastsPlos OneIF 3.234赵建宁2015109e01377745Expression of XBP1s in Fibroblasts is Critical for TiAl6V4 Particle-Induced RANKL Expression and OsteolysisJournal of Orthopaedic ResearchIF 2.986赵建宁2015 ONLINE6Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanismInt J Clin Exp PatholIF 1.891赵建宁2015855044-50527The flavonoid ampelopsin inhibited cell growth and induced apoptosis and G0/G1 arrest in human osteosarcoma MG-63 cells in vitroPharmazieIF 1.052赵建宁2015706388-3938Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaking pathwayMolecular medicine reportsIF 1.554赵建宁20151211499-15059Inhibition of Microtubule Dynamics Affects Podosome Belt Formation During Osteoclast InductionCell Biochemistry and BiophysicsIF 1.68赵建宁2015712741-74710Expression and clinical significance of cyclooxygenase-2 and microRNA-143 in osteosarcomaExperimental and therapeutic medicineIF 1.269赵建宁2015962374-237811A single nucleotide polymorphism in the TGF-B1 gene(rs1982073C>T)may contribute to increased risks of bone fracture,osteoporosis,and osteoarthritis:a meta-analysisClin rheumatol IF 1.696赵建宁20143632059-206412Exchanging reamed nailing versus augmentative compression plating with autogenous bone grafting for aseptic femoral shaft nonunion: A retrospective cohort studyEditorial ManagerIF 0.614赵建宁2015496668-67513Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic ratsBioscience ReportsIF 2.637赵建宁201535494-10014Endoplasmic reticulum stress-mediated inflammatory signalingpathways within the osteolytic periosteum and interfacemembrane in particle-induced osteolysisCell and Tissue ResearchIF 3.565赵建宁2015 15Anxiolytic-like effects of translocator protein(TSPO) ligand ZBD-2 in an animal model ofchronic painMolecular pain IF 3.654赵建宁2015 16Osteoprotective effects of estrogen membrane receptor GPR30 in ovariectomized ratsThe journal of steroid Biochemistry and Molecular BioiogyIF 3.628赵建宁2015154 237-24417Associations of poiymorphisma in the bone morphogenetic protein-2 gene with risk and prognosis of osteosarcoma in a Chinese populationTumor Bio IF 3.611l赵建宁20153632059-206418Comparing Accuracy of Cervical Pedicle Screw placement between a Guidance System and Manual Manipulation:A Cadaver studyMed Sci MonitIF 1.433赵建宁2015 212672-267719Sox4 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cell via activation of long noncoding RNA DANCRJournal of Molecular Histology IF 1.815赵建宁2015466467-47320Tumor-Suppressing Effects of miR-141 in Human OsteosarcomaCell Biochemistry and Biophysics IF2.38赵建宁201469 319-32521Tumor- Suppressing Effects of miR-451 in Human OsteosarcomaCell Biochemistry and Biophysics IF2.38赵建宁201470 215-22422Down-Regulation of miR-3928 Promoted Osteosarcoma GrowthCell Biochemistry and Biophysics IF2.38赵建宁201469 163-16823Learning Curve of Full-Endoscopic Technique Through Interlaminar Approach for L5/S1 DISK herniationsCell Biochemistry and Biophysics IF2.38赵建宁201433 1547-155624Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation PatientsCell Biochemistry and Biophysics IF2.38赵建宁201418 1069-107225Quantitative Assessment of the Association Between HDMX Polymorphism and SarcomaCell Biochemistry and Biophysics IF2.38赵建宁201415 8577-857926Correlation of Matrix Metalloproteinases-1 and Tissue Inhibitor of Metalloproteinases-1 with Patient Age and Grade of Lumbar Disk HerniationCell Biochemistry and Biophysics IF2.38赵建宁201470 1219-122527Research Progress on the Livin Gene and OsteosarcomasAsian Pacific Journal of Cancer Prevention IF1.5赵建宁201470 1671-167628Tumor- Suppressing Effects of miR-429 on Human OsteosarcomaCell Biochemistry and Biophysics IF2.38赵建宁201469 439-44429Down-Regulation of Adiponectin Receptors in Osteoarthritic ChondrocytesCell Biochem BiophysIF2.38赵建宁201470 491-49730MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasionTumor Biol IF2.84赵建宁201435 12743-1274831Particle-induced osteolysis mediated by endoplasmic reticulum stress in prosthesis looseningBIOMATERIALSIF 8.312赵建宁201334112611-262332Reply to comment on Bao et al.: Lesser trochanteric osteotomy in total hiparthroplasty for treating CROWE type IV developmental dysplasia of hipINTERNATIONAL ORTHOPAEDICSIF 2.319赵建宁2013375987-98733Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hipINTERNATIONAL ORTHOPAEDICS IF2.319赵建宁2013373385-390 34Free fatty acids are responsible for the hidden blood loss in total hip and knee arthroplastyMedical Hypotheses IF 1.054赵建宁20133 104-10735Significant pathways detection in Osteoporosis based on the bibliometric networkEUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES IF1.093赵建宁20131711-736MicroRNAs in osteosarcoma: From biological players to clinical contributors, a reviewJOURNAL OF INTERNATIONAL MEDICAL RESEARCH IF0.958赵建宁20134111-1237Design and preliminary biomechanical analysis of artificial cervical joint complexArchivesof orthopaedlc and traumasurgery IF1.358赵建宁20131336735-74338The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcomaFrontiers in Bioscience IF3.286赵建宁2013611384-139139CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation Cellular and molecular neuroblology IF 0.98赵建宁2013334543-54940Systematic screen with kinases inhibitors reveala kinases play distinct roles in growth of osteoprogenitor cellsInt J Clin Exp patholIF 2.242赵建宁20136102082-209141Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffoldsBiomaterials IF8.312赵建宁201134 科研课题序号项目名称项目来源经费（万）完成人起止时间1磨损微粒诱导的成骨细胞自噬在关节假体周围无菌性松动发病中的作用及机制研究81572111国家自然科学基金57赵建宁2016.1-2019.122内质网应激抑制剂4-Phenylbutyrate（4-PBA）减轻磨损微粒诱导骨溶解的机制研究南京市科研课题5赵建宁2014.1-2017.13江苏省骨科临床研究中心江苏省科技厅150赵建宁2012.5-2015.124抗假体松动骨水泥的研制及其抑制关节置换后骨溶解中的作用江苏省自然基金10赵建宁2012.7-2015.65抗假体松动骨水泥的研制及其抑制关节置换后骨溶解的机制研究军区重点课题20赵建宁2012.1-2014.12

擅长

复杂人工关节置换及翻修，股骨头坏死诊断及治疗,成人先天性髋关节脱位,关节置换术后感染,类风湿性关节炎外科治疗