赵岩

简介

辽宁省肿瘤医院 副院长，医学博士，主任医师，博士研究生导师。二级心理咨询师、临床营养师主要研究方向：消化道肿瘤的手术、化疗及靶向治疗、消化道肿瘤的发生、遗传学及其临床意义、胃肠间质瘤的综合诊治、肿瘤营养等。工作内容：胃部肿瘤的诊断和以手术为主的综合治疗。胃肠道间质瘤的诊断和综合治疗。遗传学咨询、临床营养及心理咨询。 社会任职 中华医学会肿瘤医学分会胃癌学组 委员中国临床肿瘤学会CSCO胃癌专家委员会 委员中国临床肿瘤学会CSCO胃肠间质瘤专家委员会 委员中国临床肿瘤学会CSCO肿瘤大数据专家委员会 常委中国医师协会外科分会胃肠间质瘤专业委员会 常委中国医师协会科研出版工作委员会 常委中国医师协会外科医师分会胃肠道间质瘤诊疗专业委员会 常委中国抗癌协会青年理事会 常务理事中国抗癌协会癌症筛查与早诊早治专业委员会 常务委员中国抗癌协会胃肠间质瘤专业委员会 常委中国抗癌协会肿瘤支持治疗专业委员会 委员 中国医院协会互联网健康专业委员会 委员中国卫生信息与健康医疗大数据学会 常务委员国家远程医疗与互联网医学中心医疗5G网络建设工作委员会 副主任委员 获奖荣誉 2018年，中国医师协会，人文医师2020年，辽宁省科协，优秀科技工作者2020年，辽宁省电视台，都市频道，名优主讲专家2021年，抗击疫情先进分子 科研成果 1. Oda, S., et al., Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability. Nucleic Acids Res, 2005. 33(5): p. 1628-36.2. Oda, S., Y. Zhao, and Y. Maehara, Microsatellite instability in gastrointestinal tract cancers: a brief update. Surg Today, 2005. 35(12): p. 1005-15.3. Sakurai, M., et al., High-resolution fluorescent analysis of microsatellite instability in gastric cancer. Eur J Gastroenterol Hepatol, 2007. 19(8): p. 701-9.4. Zhao, Y., et al., Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1. Gene, 2008. 423(2): p. 188-93.5. Oki, E., et al., Chemosensitivity and survival in gastric cancer patients with microsatellite instability. Ann Surg Oncol, 2009. 16(9): p. 2510-5.6. Oki, E., et al., The difference in p53 mutations between cancers of the upper and lower gastrointestinal tract. Digestion, 2009. 79 Suppl 1: p. 33-9.7. Oki, E., et al., Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer. World J Gastroenterol, 2009. 15(20): p. 2520-5.8. Ando, K., et al., High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer. Cancer Sci, 2010. 101(3): p. 639-45.9. Zhao, Y., et al., The impact of a high-frequency microsatellite instability phenotype on the tumor location-related genetic differences in colorectal cancer. Cancer Genet Cytogenet, 2010. 196(2): p. 133-9.10. Ando, K., et al., Secondary resistance of extra-gastrointestinal stromal tumors to imatinib mesylate: report of a case. Surg Today, 2011. 41(9): p. 1290-3.11. Yoshida, R., et al., Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer. Eur J Hum Genet, 2011. 19(3): p. 320-5.12. Liang, J.W., et al., Laparoscopic versus open gastric resections for gastric gastrointestinal stromal tumors: a meta-analysis. Surg Laparosc Endosc Percutan Tech, 2013. 23(4): p. 378-87.13. Nakanishi, R., et al., Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer. Int J Clin Oncol, 2013. 18(6): p. 1042-8.14. Zhang, J., et al., The heat shock protein 90 inhibitor 17-AAG suppresses growth and induces apoptosis in human cholangiocarcinoma cells. Clin Exp Med, 2013. 13(4): p. 323-8.15. Zhao, Y., et al., GSTT1 null genotype contributes to increased risk of gastric cancer in Chinese population: evidence from a meta-analysis. Tumour Biol, 2013. 34(3): p. 1691-7.16. Ando, K., et al., Mortalin is a prognostic factor of gastric cancer with normal p53 function. Gastric Cancer, 2014. 17(2): p. 255-62.17. Zhao, Y., et al., Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer. Anticancer Res, 2014. 34(10): p. 5421-7.18. Yu, T., et al., Prediction of T stage in gastric carcinoma by enhanced CT and oral contrast-enhanced ultrasonography. World J Surg Oncol, 2015. 13: p. 184.19. Zhao, Y., et al., Low-frequency microsatellite instability in genomic di-nucleotide sequences correlates with lymphatic invasion and poor prognosis in gastric cancer. Cell Biochem Biophys, 2015. 71(1): p. 235-41.20. Eto, T., et al., Modal variety of microsatellite instability in human endometrial carcinomas. J Cancer Res Clin Oncol, 2016. 142(2): p. 353-63.21. Zheng, G.L., et al., [Analysis of the therapeutic efficacy of radical gastrectomy in Siewert type and adenocarcinoma of the esophagogastric junction]. Zhonghua Zhong Liu Za Zhi, 2016. 38(7): p. 538-42.22. Zhu, H., et al., Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo. Pharm Biol, 2016. 54(2): p. 285-92.23. Zhang, B., et al., Clinicopathological characteristics and prognosis of primary appendiceal stromal tumors. World J Surg Oncol, 2018. 16(1): p. 225.24. Zhang, J., et al., Prognostic value of sorting nexin 10 weak expression in stomach adenocarcinoma revealed by weighted gene co-expression network analysis. World J Gastroenterol, 2018. 24(43): p. 4906-4919.25. Zheng, G.L., et al., [Clinical value of endoscopicultrsaonography and multi-slice spiral CT in Siewert and type adenocarcinoma of esophagogastric junction]. Zhonghua Zhong Liu Za Zhi, 2018. 40(3): p. 191-195.26. Jiang, H., et al., Circulating long non-coding RNA PCGEM1 as a novel biomarker for gastric cancer diagnosis. Pathol Res Pract, 2019. 215(10): p. 152569.27. Meng, X., et al., Neoadjuvant Chemoradiation Treatment for Resectable Esophago-Gastric Cancer: A Systematic Review and Meta-Analysis. J Cancer, 2019. 10(1): p. 192-204.28. Meng, X., et al., Comprehensive analysis of histone modification-associated genes on differential gene expression and prognosis in gastric cancer. Exp Ther Med, 2019. 18(3): p. 2219-2230.29. Wang, Y., et al., Implication of lymph node staging in migration and different treatment strategies for stage T2N0M0 and T1N1M0 resected gastric cancer: a SEER population analysis. Clin Transl Oncol, 2019. 21(11): p. 1499-1509.30. Xu, X., et al., Is pathologic tumor regression grade after neo-adjuvant chemotherapy a promising prognostic indicator for patients with locally advanced gastric cancer? A cohort study evaluating tumor regression response. Cancer Chemother Pharmacol, 2019. 84(3): p. 635-646.31. Zhang, J., et al., ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1. J Physiol Biochem, 2019. 75(3): p. 379-389.32. Zhang, J., et al., P4HB, a Novel Hypoxia Target Gene Related to Gastric Cancer Invasion and Metastasis. Biomed Res Int, 2019. 2019: p. 9749751.33. Zhang, J., et al., Hypoxia-induced LncRNA PCGEM1 promotes invasion and metastasis of gastric cancer through regulating SNAI1. Clin Transl Oncol, 2019.34. Dong, Z., et al., USP19 Enhances MMP2/MMP9-Mediated Tumorigenesis in Gastric Cancer. Onco Targets Ther, 2020. 13: p. 8495-8510.35. Dong, Z., et al., Identification of Hub Genes in Gastric Cancer with High Heterogeneity Based on Weighted Gene Co-Expression Network. Crit Rev Eukaryot Gene Expr, 2020. 30(2): p. 101-109.36. Meng, X., et al., Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma. Biomed Res Int, 2020. 2020: p. 8657468.37. Tong, Y., et al., Tumor Regression Grade Predicts Survival in Locally Advanced Gastric Adenocarcinoma Patients with Lymph Node Metastasis. Gastroenterol Res Pract, 2020. 2020: p. 3435673.38. Wang, Y., et al., A SEER population analysis of stage IB resected gastric cancer: who can benefit from adjuvant therapy? Scand J Gastroenterol, 2020. 55(2): p. 193-201.39. Wang, Y., et al., Indications of neoadjuvant chemotherapy for locally advanced Gastric Cancer patients based on pre-treatment clinicalpathological and laboratory parameters. J Cancer, 2020. 11(20): p. 6000-6008.40. Yang, D., et al., Patient-generated subjective global assessment versus nutritional risk screening 2002 for gastric cancer in Chinese patients. Future Oncol, 2020. 16(3): p. 4475-4483.41. Zhang, J., et al., LINC00163 inhibits the invasion and metastasis of gastric cancer cells as a ceRNA by sponging miR-183 to regulate the expression of AKAP12. Int J Clin Oncol, 2020. 25(4): p. 570-583.42. Zhang, T., et al., LncRNA PCGEM1 enhances metastasis and gastric cancer invasion through targeting of miR-129-5p to regulate P4HA2 expression. Exp Mol Pathol, 2020. 116: p. 104487.43. Zheng, G., et al., Clinicopathological Features, Treatment Strategy, and Prognosis of Primary Non-Hodgkin's Lymphoma of the Duodenum: A SEER Database Analysis. Can J Gastroenterol Hepatol, 2020. 2020: p. 9327868.44. Cui, H., et al., Chemotherapeutic potency stimulated by SNAI1-knockdown based on multifaceted nanomedicine. J Control Release, 2021. 337: p. 343-355.45. Guo, S., et al., The assessment of the optimal number of examined lymph nodes and prognostic models based on lymph nodes for predicting survival outcome in patients with stage N3b gastric cancer. Asia Pac J Clin Oncol, 2021. 17(2): p. e117-e124.46. Meng, X., et al., Totally Laparoscopic Gastrectomy Versus Laparoscopic-Assisted Gastrectomy for Gastric Cancer: A Systematic Review and Meta-Analysis. J Laparoendosc Adv Surg Tech A, 2021. 31(6): p. 676-691.47. Tong, Y., et al., Evaluation and Comparison of Predictive Value of Tumor Regression Grades according to Mandard and Becker in Locally Advanced Gastric Adenocarcinoma. Cancer Res Treat, 2021. 53(1): p. 112-122.48. Wang, Y., et al., What is behind the fear of cancer during menopausal hormone therapy in China? Arch Gynecol Obstet, 2021.49. Zheng, G.L., et al., Surgical resection of esophagogastric junction stromal tumor: How to protect the cardiac function. World J Gastroenterol, 2021. 27(9): p. 854-865. 进修经历 2004年4月-2005年3月九州大学辅导医生：Maehara Yoshihiko 1999年6月-1999年8月九州癌中心辅导医生：Baba Hideo 工作经历 2016年8月-至今辽宁省肿瘤医院副院长 2015年10月-至今辽宁医学杂志社编辑部主任 2015年8月-至今辽宁省肿瘤医院主任医师 1998年8月-2016年8月辽宁省肿瘤医院医生 教育经历 博士日本九州大学外科学 硕士中国医科大学肿瘤学 本科大连医科大学临床医学

擅长

胃癌 胃肠间质瘤 其它胃部肿瘤肿瘤遗传学咨询